Case Studies

Biomedical Analysis

Oxidative Induction Time Measures Active Antioxidants CPG discovered a method of determining trace amounts of active antioxidant in oxidatively stabilized polyethylene.  Findings published in the Journal of Biomedical Materials Research.


Annulus Fibrosus Tissue Model Leveraging strong hydrogel and custom test design expertise, CPG developed a composite structure that simplifies fatigue testing of nucleus pulposus replacements.

Synthetic Tissue Models for Medical Device Development. Includes example of hydrogel arterial model stiffened to match the compliance of human aortas. The use of synthetic materials to replace tissues enables the ability to test over substantially extended periods without concern for natural variability or tissue degradation.

Root-Cause and Failure Analysis

Artificial Lens Hazing Root Cause Analysis A client of Cambridge Polymer Group had concerns over hazing that was occurring in a new formulation of lenses during manufacture. CPG traced the cause of the cloudiness to a poorly controlled reaction process resulting in microcavitation within the lens during the swelling process as the lens hydrated.

Cleanliness Assessment of Medical Devices  This case highlights how changes in manufacturing processes can impact biocompatibility.

Failure Analysis in Catheters A client presented catheter hubs that appeared to be cracking during their manufacturing process. Cambridge Polymer Group isolated the root cause and proposed an alternative manufacturing strategy that the client adopted.