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Author Archives: Dr. Stephen Spiegelberg

  1. Flamingos Doing Vector Calculus

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    While we’ve previously celebrated the kitschy charm of plastic flamingos, today we turn our attention to the remarkable living birds and the science behind their mesmerizing feeding behaviors. With their beaks and most of their heads submerged near their feet, the birds stomp their feet in a rhythmic manner while chattering their beaks. But what exactly are they doing beneath the surface?

    Unlocking the Flamingo’s Secret Techniques

    Driven by curiosity, Víctor Ortega-Jiménez from the University of Maine, alongside collaborators from Georgia Tech and Kennesaw State University, decided to find out. Using detailed, 3D-printed models of flamingo heads, the team recreated and analyzed the birds’ signature feeding actions. Their findings, published in the Proceedings of the National Academy of Sciences (PNAS) in May 2025, finally unveiled the sophisticated strategies flamingos use to feed—movements that have captivated both bird enthusiasts and scientists for years.

    The Dance That Drives Dinner

    Flamingos perform a sort of underwater ballet: spinning and stomping their webbed feet in circles, stirring up the muck below. Far from random, this “wading dance” is a carefully choreographed routine designed to conjure swirling currents—vortices—that lift shrimp and other tiny morsels from the lakebed. The circular motion funnels these snacks into the water column, right where the flamingo’s beak can reach them.

    Beak Work: Precision and Power

    With their heads submerged, flamingos rapidly chatter their beaks up to a dozen times per second while their tongues pulse in sync. This rapid-fire action generates suction and whirlpools, channeling food particles toward the beak’s tip. As flamingos sweep their beaks backwards, these miniature vortices gather prey, making each mouthful more efficient.

    The Grand Finale: The Head Lift

    Every so often, flamingos abruptly lift their heads, creating a final swirl of water that draws even more food upward. This dynamic combination of footwork, beak action, and sudden head movements transforms the flamingo into an active predator, not just a passive filter feeder. Every part of their anatomy—from flexible feet to uniquely shaped beaks—works in concert to manipulate water and maximize their feeding success. These birds have studied and mastered complex chaotic fluid mechanic predictions, something that engineers sweat in their final years of undergraduate degrees.

    Inspiration for Technology

    The lessons learned from flamingo feeding could spark innovations in water filtration, microplastic collection, and aquatic robotics. By mimicking how flamingos harness fluid dynamics, engineers might develop new ways to capture tiny particles from water, offering nature-inspired solutions to modern challenges.

    See Flamingos in Action

    For those eager to witness these pink mathematicians at work, check out the videos and supplementary materials in the PNAS journal article.

     

  2. Potential Changes to the Generally Recognized as Safe (GRAS) Program

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    Background: The GRAS Framework

    The Food Additives Amendment to the Federal Food, Drug, and Cosmetic Act (FD&C Act) was established by Congress in 1958. In the Code of Federal Regulations, the rules that the FDA applies to food additives are spelled out in sections 21 CFR 170.3 and 170.30. A food additive is considered to be any substance that is intentionally added to food or may reasonably be expected to become a component of food, such as leachable components from packaging. These additives are required to be reviewed and approved by the FDA before the additives can be used in food products as part of a premarket approval process.

    However, there are exceptions to this review requirement. If the substance is Generally Recognized by qualified experts As having been adequately shown to be Safe (GRAS) under the conditions of its intended use, the substance does not require FDA approval and is not considered a food additive. GRAS assessment can be performed through scientific analysis, or from safe historical consumption of the substance if it has been used in food prior to 1958.

    The Self-Affirmation Pathway and Its Controversy

    Since 2016, the FDA has operated a voluntary GRAS notification program.  Under this system, any qualified individual can notify the FDA that a substance is not subject to the premarket approval process as it is considered GRAS. The FDA may not question the basis for the GRAS conclusion, or it may conclude that there is insufficient information to make a GRAS conclusion.

    Although the FDA had a GRAS affirmation process in place around 1972, it was discontinued by 1997 due to lack of resources and was replaced with the notification process. The FDA maintains a GRAS database of notifications. The GRAS list, which is not comprehensive, is located in 21 CFR 182, 184, and 186.[1] Notably, the GRAS notification process is voluntary, and does not require either notification or affirmation from the FDA.

    This self-affirmation pathway has been criticized as a “loophole,” enabling manufacturers to introduce new food ingredients without sufficient safety data or transparency. While the process allows for efficiency and rapid market entry, it also means that the FDA and consumers may be unaware of new substances in the food supply.

    Proposed Changes in 2025

    In March 2025, the Health and Human Services secretary directed the FDA to consider removing the self-affirmation process of the GRAS program.[2] Companies would need to publicly notify the FDA of their intended use of substances in food products, along with safety data, before they could go to market with the substances. This substantial change in legislation would require many companies to re-evaluate their safety data and may require retroactive approval from the FDA.

    Current vs. Proposed GRAS Process

    AspectCurrent GRAS ProgramProposed Changes (2025)
    FDA NotificationVoluntaryMandatory
    Public DisclosureNot requiredRequired
    FDA Premarket ReviewNot requiredRequired
    Industry BurdenLowerHigher
    TransparencyLimitedEnhanced
    Time to MarketShorterLonger

    Implementing these changes will not be immediate. The FDA must conduct formal rulemaking, and because the GRAS exemption is written into federal law, Congressional action may be required. These steps could take years and may face industry resistance and legal challenges.

    Establishing Safety Profiles for Food Additives

    • Deliberately Added Ingredients: Toxicological evaluation of the ingredients based on the chemistry and amount can assist in establishing the safety profile.
    • Inadvertent Additives (e.g., from Packaging): Inadvertent food additives may be introduced from materials contacting food products, including food processing equipment, containers, or food preparation surfaces. In these cases, substances may diffuse into the food from the contact materials, which are often plastic and may contain antioxidants, colorants, plasticizers, and other stabilizers. For these substances, migration testing needs to be performed using food simulants to assess the amount of substance that is anticipated to be incorporated into the food product. This testing is comparable to leachables/extraction testing performed for medical devices.

    Contact Cambridge Polymer Group for questions about migration testing in plastic products used in food contact.

    [1] https://www.fda.gov/food/generally-recognized-safe-gras/gras-notice-inventory

    [2] https://www.hhs.gov/press-room/revising-gras-pathway.html

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