Presentations

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Click on the following links to view presentations given by researchers at Cambridge Polymer Group, Inc.

Interfacial Porosity in Bone Cement

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Analysis of the conditions that lead to extensive interfacial porosity in bone cement (presented at Orthopaedic Research Society Annual Conference, 1999)

Analysis of the Transient Behavior of Biopolymers with DSC and Rheology

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Analytical techniques used to monitor bone cement curing are discussed, along with a background in total hip replacement surgery (presented at the Midwestern Thermal Analysis Forum, 1999).

Analytical Techniques for Assessing the Effects of Radiation on UHMWPE

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This presentation outlines some of the techniques used to quantify chemical, mechanical, and morphological effects of ionizing radiation on ultra-high molecular weight polyethylene (presented at Society for Biomaterials Annual Conference, Polyethylene Short Course, St. Paul, MN 2001)

A Technique for Characterizing Complex Polymer Solutions in Extensional Flows

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The technique of capillary breakup rheometry is discussed, and how it can be used to examine associating polymer solutions (presented at the 72nd Meeting of the Society of Rheology, Hiltonhead, SC, 2001)

Crosslink Density Measurements in UHMWPE

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The theory and techniques used to measure crosslink density in ultrahigh molecular weight polyethylene are discussed (presented at the UHMWPE Symposium, ASTM Meeting, Phoenix, AZ 2001).

Capillary Breakup To Determine the Extensional Properties of Polymeric Fluids

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Capillary breakup rheometry is used to measure the extensional properties of hyaluronic acid and polyethylene oxide with different salt loadings (presented at the Northeastern Meeting of the American Chemical Society, Durham, NH 2001).

Rheology of Hagfish Mucins

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The rheology of the mucous obtained from hagfish is presented, along with a discussion of the effects of the rheological response on the defense mechanism of this fish. (presented at the Society for Rheology Annual Meeting, October 13-16, 2003, Pittsburgh, PA)

Assessing the Cleanliness of Medical Devices

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Summary: A series of case studies on cleanliness issues in biomedical devices are discussed. This talk was presented at the 3rd Annual Orthopaedic Manufacturing & Technology Exposition and Conference in Chicago, IL on June 20th, 2007.

An injectable hydrogel for nucleus pulposus augmentation

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Summary: This presentation discusses a novel hydrogel formulation invented by researchers at Cambridge Polymer Group, and its use as an injectable replacement for a degenerated nucleus pulpulsus.

Oxidation induction time to assess antioxidant efficacy

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This paper discusses the use of oxidation induction time to screen potential antioxidants for their oxidation-prevention efficacy in thermoplastics such as polyethylene. This paper was presented at the 56th annual meeting of the Orthopedic Research Society in 2010.

Cleanliness of Biomedical Devices

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CPG researcher Stephen Spiegelberg presented case studies on the impact of the cleanliness of implantable biomedical devices, as well as recent ASTM activities in the area, at the 2010 Medical Grade Plastics conference in Philadelphia, PA.

Rheological characterization of materials for biomedical application

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This presentation discusses the rheological characterization of acrylic-based bone cement used for total hip and knee replacement surgeries, and outlines how the rheology may be used to improve the cement properties. Presented at the TA Instruments User Conference in Newport, RI in 2006.

Refuse to Fuse: Development of an injectable nucleus pulposus replacement

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This presentation by Gavin Braithwaite discusses CPG's development of a hydrogel-based technology for augmenting or replacing the natural nucleus pulposus in the intervertebral disc of the spine. Presented at the Northeastern Bioengineering Conference at Brown University in 2008.

Engineering biomedical materials: From total joints to tissue sparing

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In this plenary talk presented at the University of Birmingham (UK) in April, 2011, Dr. Gavin Braithwaite discusses the thought process behind designing medical implants. In his analysis, he presents information on polyethylene and hydrogel implants designed at Cambridge Polymer Group.

Injectable Poly(vinyl alcohol) Hydrogels for Nucleus Replacement

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A poster presentation on an injectable hydrogel system developed at Cambridge Polymer Group for nucleus pulposus replacement, presented at the Spine Arthroplasty Society meeting in 2008 in Miami, Fl.

In vitro testing of injectable PVA nucleus replacement hydrogels

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A poster presentation on the in vitro testing of hydrogel based nucleus pulposus replacement technology developed at Cambridge Polymer Group. Presented at the Spine Arthroplasty Society meeting in London, 2009.

Towards an artificial functional spinal unit for long-term in vitro testing

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Presented at the 2010 Orthopedic Research Society meeting, this poster presents the development and in vitro testing of a hydrogel-based annulus fibrosis model intended for long-term mechanical studies.

Absorption of Physiologically Relevant Compounds in UHMWPE

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Presented at the 2011 Orthopedic Research Society meeting, this paper presents the results of a study of absorbed biological fluids into conventional and Vitamin E stabilized UHMWPE for orthopedic applications.

Oxidative Stability of Highly Crosslinked Vitamin E UHMWPE in Extreme and Physiological Accelerated Aging Conditions

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Presented at the 2011 Orthopedic Research Society meeting, this paper discusses accelerated aging analysis of Vitamin E stabilized UHMWPE for orthopedic applications.

Sensitive Measurement of Vitamin E Concentration using OIT

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Presented at the 2011 Orthopedic Research Society meeting, this paper discusses the quantification of Vitamin E in stabilized UHMWPE for orthopedic applications.

FDA Workshop on Reprocessing Medical Devices

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The FDA hosted a two day workshop on June 8-9, 2011 on issues involving reprocessing reusable medical devices, such as endoscopes and arthroscopic shavers. CPG researcher Stephen Spiegelberg presented the areas in which ASTM has been involved with guidance documents and standards for cleaning assessment and validation.

Absorption of Biological Compounds into UHMWPE

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The influence of polyethylene composition on absorption of biologically-relevant species was analyzed in this study, presented at the UHMWPE Conference at Drexel University on September 22nd, 2011. The results suggest that Vitamin E may act as an inhibitor to diffusion of some biological species into UHMWPE.

The measurement of antioxidant efficacy in UHMWPE

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Oxidation induction time was used to measure the efficacy of antioxidants in UHMWPE. This technique was used to analyzed the efficacy of a variety of antioxidants, and provides a useful tool for screening potential antioxidant compositions. This paper was presented at the UHMWPE conference at Drexel University on September 22, 2011.

The influence of aging environment on Vitamin E stabilized UHMWPE

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A variety of accelerated aging environments were investigated to assess their influence on the oxidation potential of Vitamin E-stabilized, highly crosslinked UHMWPE. This paper was presented at the UHMWPE conference at Drexel University on September 22, 2011.