Chromatography Analytical Chemist

Cambridge Polymer Group is seeking a full-time analytical chemistry development for immediate hire.

The successful candidate will be expected to work in the laboratory on a variety of multi-disciplinary projects as a key member of the chromatography and analytical chemistry testing team at CPG. 

We are particularly looking for a candidate with a proven track record of developing and implementing robust methods for non-targeted and targeted chemical analyses in a diverse set of matrices. The successful candidate will have experience working with a variety of sample preparation workflows (e.g. extractions, simulated leaching conditions, derivatizations), as well as expertise in optimizing separations and mass spec detection conditions.

Throughout these activities, the candidate should be deeply familiar with implementing analytical quality best practices and experimental controls to ensure the highest level of confidence in reported results. The candidate should have a strong understanding of the selection and use of system suitability standards, continuing calibration checks, positive/negative controls, spike recovery standards, surrogate standards, internal standards, replicate preparations, and trending/control charts.

Examples of typical projects include medical device chemical risk assessment, polymer resin deformulation, molecular weight assessment, root cause analysis, impurity screening, and quantitation of material additives or residual processing aids.

The successful candidate will be experienced in the operation and development of either GC-MS or LC-MS methods (not necessarily both). Experience in GPC and GPC-MALLS is a plus.

The candidate will be expected to work both independently and in project teams, under the guidance of a Senior Research Scientist.

Primary tasks include:

  • (Semi) Quantitative analytical method development and validation for both targeted and non-targeted assays
    • Focus on analytical quality through incorporation of appropriate verification/validation activities and experimental controls
    • Identification of candidate analytical conditions given target analytes or problem statement, based on literature review or analyte physical properties.
    • Sample preparation selection and execution by solvent extraction, SPE, L/L extractions, etc.
    • Method optimization and characterization for LOD/LOQ, sensitivity, resolution, repeatability, precision, carryover etc.
  • Critical analysis of data generated by other personal
    • Provide a resource for secondary analysis/review of data with a particular emphasis on critical thinking
  • Routine chromatography (GPC/SEC, GC, LC) and mass spec operation.
    • Hardware configuration, detector verification, system diagnostics
    • Sample loading, sequence queuing, data analysis/interpretation including a familiarity with semi-quantitation and unknown compound identification workflows.
    • Experience with Agilent instruments a plus
    • Expertise in multiple chromatography techniques a plus but not required.
  • Writing qualification documents (to ICH or USP criteria), SOPs and training staff to newly developed methods
  • Documentation, data/method/library organization, report generation, and clear communication of results

Our Ideal Candidate

The ideal candidate should hold at least a B.Sc. or M.Sc. in Analytical Chemistry, Chemical Engineering, or equivalent work experience. 2-5 years (depending on degree level) of experience in one or more of the following areas is preferred:

  • Contract R&D or CRO/CDMO lab
  • Extractables & leachables (E&L) or chemical characterization lab
  • Failure analysis lab
  • Environmental lab
  • Forensic Lab
  • Manufacturing QC lab
  • Academic analytical lab with substantial throughput
  • Pharma or startup analytical lab

The candidate should be comfortable working in a small, adaptable research company focused on non-routine, high-quality and rapid projects. The candidate should also be capable of working to timelines and strict protocols in support of medical device and pharmaceutical regulatory environment.

About CPG

Cambridge Polymer Group, Inc. (“CPG”) is a contract research laboratory with over 20 years’ experience providing consulting, material/product development, and analytical testing services for clients worldwide with a particular focus in the area of polymeric materials. Headquartered in Boston, MA, our employees cover a broad range of scientific fields, including chemical, electrical, biomedical and mechanical engineering, materials science, and biology. CPG’s core competencies include failure analysis, chemical risk assessment, non-standard test method development, radiation chemistry, rheology, material property enhancement, and hydrogels, as well as medical device development support.  We work with clients in a range of industries including medical devices, pharmaceutical, aerospace, automotive, resin manufacturers and processors, consumer products, gels, adhesives, food products, and inks.   We are ISO 9001:2015 certified, ISO 17025:2005 accredited, and registered with the FDA.

Send Us Your Resume

Please submit your resume and cover letter to hr@campoly.com. Cambridge Polymer Group is an equal opportunity employer.